Ischemia-free liver transplantation improves the prognosis of recipients using functionally marginal liver grafts.

Shuai WangXiaohong LinYunhua TangYichen LiangMin ZhangZhonghao XieYiwen GuoYuqi DongQiang ZhaoZhiyong GuoDongping WangXiaoshun HeWeiqiang JuMaogen Chen

Published in: Clinical and molecular hepatology (2024)

FML is a more important negative prognostic parameter than other marginal liver parameters. IFLT might ameliorate liver injury in FMLs by inhibiting the infiltration of NK cells, consequently leading to the abortion of IL-32, which drives pyroptosis in monocytes and macrophages.

Keyphrases

liver injury
drug induced
nk cells
signaling pathway
dendritic cells
peripheral blood