Risk of infections in patients treated with ticagrelor vs. clopidogrel: a systematic review and meta-analysis.

Hang Long LiQi FengMan Fung TsoiYue FeiBernard M Y Cheung

Published in: European heart journal. Cardiovascular pharmacotherapy (2022)

Compared to clopidogrel, ticagrelor reduces the risk of pneumonia, but not URTI, UTI, or sepsis. Our study provides further evidence for recommending ticagrelor to patients with acute coronary syndrome at risk of pneumonia, although the mechanism by which ticagrelor reduces the risk of pneumonia merits further research.

Keyphrases

acute coronary syndrome
percutaneous coronary intervention
antiplatelet therapy
st segment elevation myocardial infarction
st elevation myocardial infarction
coronary artery disease
community acquired pneumonia
respiratory failure
intensive care unit
urinary tract infection