Silica bound co-pillar[4+1]arene as a novel supramolecular stationary phase.
Subbareddy MekapothulaMatthew A AddicoatElisabetta A M VerderioJohn D WallisPeter J CraggGareth W V CavePublished in: Chemical communications (Cambridge, England) (2020)
A novel co-pillar[4+1]arene incorporating two bromo-octyl substituents has been synthesised for the first time, using microwave irradiation in high yield (88%) in under four minutes, and bound to the surface of chromatographic silica particles. The resulting new stationary phase has been successfully utilised to separate xylene isomers via liquid chromatographic techniques.