EEF1A2 interacts with HSP90AB1 to promote lung adenocarcinoma metastasis via enhancing TGF-β/SMAD signalling.

Liqing JiaXiaolu GeChao DuLinna ChenYanhong ZhouWei XiongJuanjuan XiangGuiyuan LiGaoming XiaoLi FangZheng Li

Published in: British journal of cancer (2021)

These findings underscore the molecular functions of EEF1A2 in LUAD metastasis and indicate that EEF1A2 represents a promising target in the treatment of aggressive LUAD.

Keyphrases

transforming growth factor
epithelial mesenchymal transition
heat shock protein
heat stress
heat shock
combination therapy
single molecule
signaling pathway
replacement therapy