Evaluation of patients with advanced epithelial ovarian cancer before primary treatment: correlation between tumour burden assessed by [18F]FDG PET/CT volumetric parameters and tumour markers HE4 and CA125.

Ariel GlickmanPilar ParedesNúria Carreras-DiéguezAida Niñerola-BaizánLydia GabaJaume PahisaPere FustéMarta Del PinoBerta Díaz-FeijóoEduardo González-BosquetNúria AgustíNuria Sánchez-IzquierdoDavid FusterAndrés PerissinottiInmaculada RomeroEsther Fernández-GalánJosep Lluís CarrascoBlanca Gil-IbáñezAureli Torné

Published in: European radiology (2021)

• In patients with high-grade advanced ovarian epithelial carcinoma, both CA125 and HE4 correlate to whole-body tumour burden assessed by PET/CT before primary treatment. • HE4 estimates peritoneal disease much better than CA125. • PET/CT volumetric parameters arise as feasible tools for the objective assessment of tumour load and its anatomical distribution.

Keyphrases

pet ct
high grade
positron emission tomography
risk factors
computed tomography
protein kinase