Macrophage Depletion Protects Against Cisplatin-Induced Ototoxicity and Nephrotoxicity.

Cathy Yea Won SungNaoki HayasePeter S T YuenJohn LeeKatharine FernandezXuzhen HuHui ChengRobert A StarMark E WarcholLisa L Cunningham

Published in: bioRxiv : the preprint server for biology (2023)

Macrophage ablation using PLX3397 was protective against cisplatin-induced ototoxicity and nephrotoxicity by limiting platinum accumulation in the inner ear and kidney.

Keyphrases

adipose tissue
drug induced
radiofrequency ablation