Case-control study of corneal topography and specular microscopy parameters in JIA patients with and without ocular involvement.
Aslıhan Yılmaz ÇebiOğuzhan KılıçarslanOzgur KasapcopurDidar UçarPublished in: International ophthalmology (2022)
Corneal astigmatism, as well as anterior and posterior elevation values, were all higher in JIA-U patients. Endothelial cell density and morphology, on the other hand, did not differ significantly between groups. Chronic inflammation's impact on stromal remodelling could explain these corneal alterations. The positive correlation between posterior elevation and the number of flares and duration of inflammation represents the importance of early diagnosis and effective treatment.
Keyphrases
- optical coherence tomography
- oxidative stress
- end stage renal disease
- wound healing
- ejection fraction
- newly diagnosed
- juvenile idiopathic arthritis
- endothelial cells
- chronic kidney disease
- prognostic factors
- peritoneal dialysis
- mass spectrometry
- patient reported outcomes
- systemic lupus erythematosus
- label free
- drug induced
- high glucose
- replacement therapy
- smoking cessation