Differential methylation of imprinting genes and MHC locus in 22q11.2 deletion syndrome-related schizophrenia spectrum disorders.

Miri CarmelElena MichaelovskyRonnie WeinbergerAmos FrischEhud Mekori-DomachevskyDoron GothelfAbraham Weizman

Published in: The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry (2020)

The differential methylation in imprinting genes and in chr6p21-22 indicate the neurodevelopmental nature of 22q11.2DS-related SZ and the major role of MHC locus in the risk to develop SZ.

Keyphrases

genome wide
dna methylation
bioinformatics analysis
genome wide association study
transcription factor
genome wide analysis
congenital heart disease