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Morphologically defined substages of tail morphogenesis in C. elegans males.

Karin KiontkePorfirio FernandezAlyssa WoronikDavid H A Fitch
Published in: bioRxiv : the preprint server for biology (2024)
Our analysis answers two open questions about tail tip morphogenesis (TTM) by showing that one of the four tail tip cells, hyp11, remains separate while the other cells fuse with each other and with two additional tail cells to form a ventral tail syncytium. This fusion begins early during TTM but is only completed towards the end of the process. This work provides a framework for future investigations of cell-biological factors that drive male tail morphogenesis.
Keyphrases
  • induced apoptosis
  • cell cycle arrest
  • endoplasmic reticulum stress
  • stem cells
  • minimally invasive
  • signaling pathway
  • single cell