Presynaptic Nrxn3 is essential for ribbon-synapse assembly in hair cells.

Alma JukicZhengchang LeiElizabeth R CebulKatherine PinterNatalie MosquedaSandeep DavidBasile Tarchini Katie S Kindt

Published in: bioRxiv : the preprint server for biology (2024)

Hearing and balance depend on specialized ribbon synapses that transmit sensory stimuli between hair cells and afferent neurons. We identify Nrxn3 as a key molecular player in ribbon-synapse assembly in hair cells.

Keyphrases

induced apoptosis
cell cycle arrest
endoplasmic reticulum stress
signaling pathway
oxidative stress
cell proliferation
spinal cord injury
single molecule