High-mobility group box 1 fragment ameliorates chronic pancreatitis induced by caerulein in mice.

Daiki HokkokuKazuki SasakiShogo KobayashiTakashi ShimboTomomi KitayamaSho YamazakiYukari YamamotoYuya OuchiHiroki ImamuraTakeshi KadoKeisuke ToyaWataru FujiiYoshifumi IwagamiDaisaku YamadaYoshito TomimaruTakehiro NodaHidenori TakahashiKatsuto TamaiYuichiro DokiHidetoshi Eguchi

Published in: Journal of gastroenterology (2024)

These findings highlight the potential of the HMGB1 fragment as a therapeutic target for the treatment of CP.

Keyphrases

transcription factor
mouse model
high fat diet induced
binding protein
type diabetes
metabolic syndrome
adipose tissue
combination therapy
human health
risk assessment
insulin resistance