Pulmonary hemorrhage in dengue: differential diagnosis with acute viral respiratory syndromes including COVID-19.
Leonardo Antonio AguiarAna Carolina de Morais Oliveira-ScusselJerônimo Coelho de MenezesPriscila Barbosa IdalóLara Élida Guazzeli de FreitasLuzia Beatriz Ribeiro ZagoCristina da Cunha Hueb Barata de OliveiraNaiara Clemente TavaresEdward José de OliveiraMarcos Vinícius da SilvaLuciana de Almeida Silva TeixeiraPublished in: Revista do Instituto de Medicina Tropical de Sao Paulo (2022)
Clinical similarities among viral diseases become even more relevant considering the current scenario, especially in Brazil, where there is a high incidence of these diseases and overlapping seasonality. We report the case of a patient with acute clinical manifestations composed of predominant respiratory symptoms and alveolar hemorrhage in which three etiologies (dengue, influenza and COVID-19) were investigated concomitantly. Only the diagnosis of dengue was confirmed. Then, the patient's immunological profile in response to stimulation of mononuclear cells with dengue virus antigen was analyzed in an attempt to identify specific characteristics that could be associated with the clinical manifestation.
Keyphrases
- dengue virus
- zika virus
- sars cov
- aedes aegypti
- coronavirus disease
- liver failure
- case report
- respiratory failure
- induced apoptosis
- drug induced
- pulmonary hypertension
- respiratory syndrome coronavirus
- aortic dissection
- cell cycle arrest
- intensive care unit
- respiratory tract
- depressive symptoms
- mass spectrometry
- physical activity
- signaling pathway
- extracorporeal membrane oxygenation