Influence of tedizolid on the cytokine response to the endotoxin challenge in healthy volunteers: a cross-over trial.

Anselm JordaBeatrix WulkersdorferChristian SchörgenhoferPeter Matzneller Valentin Al JalaliMartin BauerMichael Wölf-DuchekEdith LacknerChristoph DornBernd JilmaMarkus Zeitlinger

Published in: The Journal of antimicrobial chemotherapy (2022)

Tedizolid did not attenuate the LPS-induced cytokine response in healthy volunteers. Furthermore, endotoxaemia did not influence the plasma pharmacokinetics of tedizolid.

Keyphrases

lps induced
inflammatory response
study protocol
phase iii
phase ii