Hypertensive disorders of pregnancy and peripartum cardiomyopathy: A nationwide cohort study.
Ida BehrensSaima BasitJacob Alexander LykkeMattis F RantheJan WohlfahrtHenning BundgaardMads MelbyeHeather Allison BoydPublished in: PloS one (2019)
Although 70% of PPCM occurred in women with normotensive pregnancies, HDPs were associated with substantial increases in PPCM risk that depended on HDP severity. The heart's capacity to adapt to a normal pregnancy may be exceeded in some women already susceptible to cardiac insult, contributing to PPCM. HDPs, severe preeclampsia in particular, probably represent an additional cardiac stressor during pregnancy.