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Hypertensive disorders of pregnancy and peripartum cardiomyopathy: A nationwide cohort study.

Ida BehrensSaima BasitJacob Alexander LykkeMattis F RantheJan WohlfahrtHenning BundgaardMads MelbyeHeather Allison Boyd
Published in: PloS one (2019)
Although 70% of PPCM occurred in women with normotensive pregnancies, HDPs were associated with substantial increases in PPCM risk that depended on HDP severity. The heart's capacity to adapt to a normal pregnancy may be exceeded in some women already susceptible to cardiac insult, contributing to PPCM. HDPs, severe preeclampsia in particular, probably represent an additional cardiac stressor during pregnancy.
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