Butyrate acts as a positive allosteric modulator of serotonin transporter to decrease ileal serotonin availability.

Jieling CaiJamie CheungSamson W M CheungKarie T C ChinRicky W K LeungRonald S T LamRakesh SharmaJensen H C YiuConnie Wai Hong Woo

Published in: British journal of pharmacology (2023)

Short-term HFD may be beneficial for alleviating gastrointestinal reactions by increasing butyrate to suppress local serotonin level and providing energy to cancer patients undergoing radiation.

Keyphrases

patients undergoing
papillary thyroid
small molecule
high fat diet
squamous cell carcinoma
radiation therapy
young adults