Binding Activity Classification of Anti-SARS-CoV-2 Molecules using Deep Learning Across Multiple Assays
Bilge Eren YamasanSelcuk KorkmazPublished in: Balkan medical journal (2024)
This study demonstrates the significant impact of deep learning, particularly DNN models enhanced with SMOTE, in improving the identification of active compounds in bioassay datasets for COVID-19 drug discovery, outperforming traditional machine learning models. Furthermore, this study highlights the efficacy of advanced computational techniques in addressing high-throughput screening data imbalances.