Increased inflammation and endothelial markers in patients with late severe post-thrombotic syndrome.
Luis Fernando BittarLetícia Queiroz da SilvaFernanda Loureiro de Andrade OrsiKiara Cristina Senger ZapponiBruna de Moraes MazettoErich Vinícius de PaulaSilmara Aparecida de Lima MontalvãoJoyce Maria Annichino-BizzacchiPublished in: PloS one (2020)
DVT patients present an inflammatory status, endothelial dysfunction and altered proteolysis MMPs activity, even a long time after the acute thrombotic episode, which is more significant in severe PTS. These results suggest a possible role of these mediators in the maintenance and worsening of PTS severity.