Effect of Genetic Variations in Drug-Metabolizing Enzymes and Drug Transporters on the Pharmacokinetics of Rifamycins: A Systematic Review.

Tesemma Sileshi Gosaye Mekonnen Tefera Eyasu Mekonnen Eshetu Eleni Aklillu

Published in: Pharmacogenomics and personalized medicine (2022)

The pharmacokinetics of rifamycins is influenced by genetic variation of drug-metabolizing enzymes and transporters. Controlled clinical studies are, however, required to establish these relationships.

Keyphrases

drug induced
emergency department
genome wide
gene expression
copy number
electronic health record