Using Skin Bioengineering to Highlight How Weight and Diabetes Mellitus Modify the Skin in the Lower Limbs of Super-Obese Patients.
Elisabetta IacopiNicola RiitanoValentina DiniRossana BertaLetizia PieruzziAgata JanowskaMarco AnselminoAlberto PiaggesiMarco RomanelliPublished in: Diabetes, metabolic syndrome and obesity : targets and therapy (2020)
Severe obesity significantly affects both shape and structure of the foot, possibly exposing these patients to a higher risk of biomechanical stress. On such a background DM, modifying skin hydration and protective mechanisms exerts a synergistic role further increasing the risk of trauma and ulcers.
Keyphrases
- obese patients
- wound healing
- bariatric surgery
- soft tissue
- weight loss
- end stage renal disease
- newly diagnosed
- ejection fraction
- chronic kidney disease
- type diabetes
- weight gain
- roux en y gastric bypass
- metabolic syndrome
- gastric bypass
- body mass index
- insulin resistance
- early onset
- prognostic factors
- glycemic control
- cancer therapy
- patient reported
- heat stress