Improvements in Posttransplant Outcomes Over Two Decades in Older Patients with Acute Myeloid Leukemia in the EBMT ALWP Study.

Ali Bazarbachi Myriam Labopin Nour M Moukalled Nicolaus M Kröger Christina Rautenberg Johannes Schetelig Juergen Finke Igor Wolfgang Blau Didier Blaise Matthias Stelljes Matthias Eder Uwe Platzbecker Peter Dreger Wolfgang Andreas Bethge Johanna Tischer David Burns Henrik Sengeløv Eolia Brissot Sebastian Giebel Arnon Nagler Fabio Ciceri Florent Malard

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2024)

In older patients with AML, we observed an impressive improvement over time in posttransplant outcomes, mostly attributed to decreased RI rather than decreased NRM, and regardless of disease status at transplant. These large-scale, real-world data can serve as a benchmark for future studies in this setting and indicate that the opportunity for transplant for the elderly should be mandatory and no longer an option.

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