Pharmacological interventions for preventing upper gastrointestinal bleeding in people admitted to intensive care units: a network meta-analysis.
Ingrid ToewsSalman HussainJohn L Z NyirendaMaria A WillisLucia KantorováSimona SlezakovaMinyahil Tadesse BoltenaPeter John VictorLuis Eduardo Santos FontesMiloslav KlugarBehnam SadeghiradJoerg Johannes MeerpohlPublished in: BMJ evidence-based medicine (2024)
Several interventions seem effective in preventing clinically important upper GI bleeding while there is limited evidence for other outcomes. Patient-relevant benefits and harms need to be assessed under consideration of the patients' underlying conditions.