Antihypersensitivity effect of betanin (red beetroot extract) via modulation of microglial activation in a mouse model of neuropathic pain.

Nichakarn KwankaewHiroaki OkudaAye Aye-MonTatsuya IshikawaKiyomi HoriPhattarapon SonthiYu KozakaiNoriyuki Ozaki

Published in: European journal of pain (London, England) (2021)

This article supports findings of the effect of betanin on NeP and provides a potential therapeutic candidate for NeP. Furthermore, elucidating the underlying mechanism of the effect of betanin on microglial activation could assist the development of new treatments for chronic pain.

Keyphrases

neuropathic pain
chronic pain
spinal cord
spinal cord injury
mouse model
inflammatory response
oxidative stress
lipopolysaccharide induced
pain management
lps induced