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Efficacy and Safety of Sitagliptin Compared with Dapagliflozin in People ≥ 65 Years Old with Type 2 Diabetes and Mild Renal Insufficiency.

Annaswamy RajiZhi Jin XuRaymond L H LamEdward A O'NeillKeith D KaufmanSamuel S Engel
Published in: Diabetes therapy : research, treatment and education of diabetes and related disorders (2020)
In patients ≥ 65 years of age with T2D and mild renal insufficiency with inadequate glycemic control on metformin ± sulfonylurea, treatment with sitagliptin for 24 weeks resulted in improvement in HbA1c relative to treatment with dapagliflozin that is consistent with that previously observed in the overall population. Both treatments were generally well tolerated.
Keyphrases
  • glycemic control
  • end stage renal disease
  • type diabetes
  • chronic kidney disease
  • newly diagnosed
  • ejection fraction
  • peritoneal dialysis
  • prognostic factors
  • blood glucose
  • combination therapy
  • metabolic syndrome