Loss of the laminin subunit alpha-3 induces cell invasion and macrophage infiltration in cutaneous squamous cell carcinoma.

Matthew P CaleyV L MartinsK MooreM LashariL NissinenV-M KähäriS AlexanderE JonesCatherine A HarwoodJ JonesM DonaldsonJ F MarshallEdel A O'Toole

Published in: The British journal of dermatology (2020)

These data provide evidence that loss of the laminin α3 chain in cSCC has an effect on both the epithelial and immune components of cSCC, resulting in an aggressive tumour microenvironment.

Keyphrases

squamous cell carcinoma
stem cells
electronic health record
adipose tissue
locally advanced
radiation therapy
artificial intelligence
data analysis
deep learning