Probing human heart TCA cycle metabolism and response to glucose load using hyperpolarized [2- 13 C]pyruvate MRS.

Hsin-Yu Chen Jeremy W GordonNicholas DworkBrian T ChungAndrew RiselliSanjay SivalokanathanRobert A BokJames B SlaterDaniel B VigneronM Roselle AbrahamPeder Eric Zufall Larson

Published in: NMR in biomedicine (2023)

C]pyruvate. Cardiac metabolite measurement in the fasting/fed states provides information on cardiac metabolic flexibility and the acetylcarnitine pool.

Keyphrases

left ventricular
blood glucose
endothelial cells
heart failure
insulin resistance
single molecule
molecular dynamics simulations
atrial fibrillation
metabolic syndrome
blood pressure
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