Sequential therapy including regorafenib for unresectable hepatocellular carcinoma: Effect of early relative changes in hepatic functional reserve after regorafenib administration on prognosis.

Hironori OchiJoji TaniTetsu TomonariTatsuya TaniguchiYohei KoizumiAkira HiroseChikara OgawaAtsushi HiraokaAkihiro MorishitaAkio MoriyaMasashi HirookaAkihiro Deguchinull Symple Study Group

Published in: Hepatology research : the official journal of the Japan Society of Hepatology (2021)

Hepatic functional reserve significantly declined after regorafenib administration. During regorafenib treatment, favorable hepatic functional reserve before administration and maintenance of favorable hepatic reserve after administration lead to prolonged prognosis.

Keyphrases

metastatic colorectal cancer
squamous cell carcinoma
bone marrow
locally advanced
combination therapy
smoking cessation