Effects of Cotadutide on Metabolic and Hepatic Parameters in Adults With Overweight or Obesity and Type 2 Diabetes: A 54-Week Randomized Phase 2b Study.

Rajaa NahraTao WangKishore M GaddeJan OscarssonMichael StumvollLutz JermutusBoaz HirshbergPhilip Ambery

Published in: Diabetes care (2021)

Cotadutide treatment for 54 weeks improved glycemic control and weight loss in participants with overweight/obesity and type 2 diabetes. Ad hoc analyses demonstrated improvements in hepatic parameters and support further evaluation of cotadutide in NASH.

Keyphrases

weight loss
glycemic control
type diabetes
bariatric surgery
roux en y gastric bypass
blood glucose
gastric bypass
weight gain
placebo controlled
double blind
insulin resistance
obese patients
metabolic syndrome
phase iii
phase ii
adipose tissue
combination therapy
physical activity
study protocol