The RNA-Protein Interactome of Differentiated Kidney Tubular Epithelial Cells.

Michael IgnarskiConstantin RillRainer W J KaiserMadlen KaldirimRené NeuhausReza EsmaillieXinping LiCorinna KleinKatrin BohlMaike PetersenChristian K FreseMartin HöhneIlian AtanassovMarkus M RinschenKatja HöpkerBernhard SchermerThomas BenzingChristoph DieterichFrancesca FabrettiRoman-Ulrich Müller

Published in: Journal of the American Society of Nephrology : JASN (2019)

These findings demonstrate the regulation of RBPs through environmental stimuli and provide insight into the biology of hypoxia-response signaling in epithelial cells in the kidney. A repository of the RBPome and proteome in kidney tubular epithelial cells, derived from our findings, is freely accessible online, and may contribute to a better understanding of the role of RNA-protein interactions in kidney tubular epithelial cells, including the response of these cells to hypoxia.

Keyphrases

endothelial cells
induced apoptosis
high glucose
protein protein
social media
healthcare
binding protein
cell cycle arrest
cell proliferation
signaling pathway
climate change
endoplasmic reticulum stress