Association of Mitochondrial DNA Genomic Variation With Risk of Pick Disease.
Rebecca R ValentinoMichael G HeckmanPatrick W JohnsonMatthew C BakerAlexandra I Soto-BeasleyRonald L WaltonShunsuke KogaShanu F RoemerEunRan SuhRyan J UittiJohn Q TrojanowskiMurray GrossmanVivianna M Van DeerlinRosa RademakersZbigniew K WszolekGourisankar GhoshOwen A RossPublished in: Neurology (2021)
Our findings indicate that mtDNA variation is not a disease driver but may influence disease susceptibility. Ongoing genetic assessments in larger cohorts of Pick disease are currently underway.