Pineoblastoma in children less than six years of age: The Head Start I, II, and III experience.
Mohamed S AbdelbakiMohammad H Abu ArjaTom B DavidsonJason R FangusaroJoseph R StanekIra J DunkelGirish DhallSharon L GardnerJonathan L FinlayPublished in: Pediatric blood & cancer (2020)
Within the HS I-III trials, CSI and HDCx/AuHCR were statistically associated with improved survival. The high PD rate during later induction cycles and following consolidation chemotherapy warrants consideration of fewer induction cycles prior to consolidation and the potential intensification of consolidation with multiple cycles of marrow-ablative chemotherapy and irradiation.