Prevalence and clinical implications of germline mutations among Jordanian patients with ovarian cancer. The Jordanian exploratory cancer genetics (Jo-ECAG) ovarian study.
Hikmat Abdel-RazeqKhansa Al-AzzamShatha ElemianHala Abu-FaresAreej Abu SheikhaHira Bani HaniRayan BaterBaha' SharafBrandie HealdEdward D EsplinSarah M NielsenMais AlkyamLama AbujamousAreej Al-AttaryPublished in: Molecular genetics & genomic medicine (2022)
PGVs are common among Jordanian women with ovarian cancer, and mostly occur in BRCA1/2. Given its clinical impact on disease prevention and precision therapy, universal testing should be routinely offered.