Tissue-mimicking thermochromic phantom for characterization of HIFU devices and applications.

Avinash ErankiAndrew S Mikhail Ayele H NegussiePrateek S KattiBradford J WoodAri Partanen

Published in: International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group (2019)

We developed a novel MR-imageable and HIFU-compatible TMTCP to characterize HIFU heating without MRI or thermocouples. The HIFU-optimized TMTCP reports absolute temperatures and ablation zone geometry with high spatial resolution. Consequently, the TMTCP can be used to evaluate HIFU heating and may provide an in vitro tool for peak temperature assessment, and reduce preclinical in vivo requirements for clinical translation.

Keyphrases

high intensity
contrast enhanced
magnetic resonance imaging
emergency department
computed tomography
cell therapy
bone marrow
adverse drug