Effect of antiplatelet and anticoagulant medication use on injury severity and mortality in patients with traumatic brain injury treated in the intensive care unit.
Juho VehviläinenJyri J VirtaMarkus B SkrifvarsMatti ReinikainenStepani BendelTero Ala-KokkoSanna HoppuRuut LaitioJari SiironenRahul RajPublished in: Acta neurochirurgica (2023)
Both antiplatelet and anticoagulant use before TBI were risk factors in our study for 1-year mortality. Antiplatelet and anticoagulation medication users had a higher radiological intracranial injury burden than non-users defined by the Helsinki CT score. Further investigation on the effect of DOACs on mortality should be done in ICU-treated TBI patients.
Keyphrases
- traumatic brain injury
- risk factors
- atrial fibrillation
- cardiovascular events
- venous thromboembolism
- newly diagnosed
- ejection fraction
- severe traumatic brain injury
- computed tomography
- healthcare
- prognostic factors
- type diabetes
- coronary artery disease
- magnetic resonance imaging
- patient reported outcomes
- contrast enhanced
- optical coherence tomography