Methylsulfonylmethane (MSM): A chemical shift reference for 1 H MRS of human brain.

Lana G KaiserDavid RussellTristan MaschmeyerRichard L RedfernBen A Inglis

Published in: Magnetic resonance in medicine (2019)

The chemical and biological properties of MSM-rapid crossing of the blood-brain barrier, water solubility, a singlet resonance resolved from metabolite resonances, chemical shift stability with respect to pH/temperature, and stable temporal presence in the brain-lead us to propose its use as a frequency reference for MRS.

Keyphrases

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