Establishment and Characterization of an Epstein-Barr Virus-positive Cell Line from a Non-keratinizing Differentiated Primary Nasopharyngeal Carcinoma.
Annie Wai Yeeng ChaiShi Mun YeeHui Mei LeeNorazlin Abdul AzizPei San YeeMarini MarzukiKa Wo WongAlan Kwok Shing ChiangLarry Ka-Yue ChowWei DaiTeng Fei LiuLu Ping TanAlan Soo-Beng KhooKwok-Wai LoPaul V H LimPathmanathan RajaduraiHoward LightfootSyd BarthorpeMathew J GarnettSok Ching CheongPublished in: Cancer research communications (2024)
NPC268 is the first and only EBV-positive cell line derived from a primary non-keratinizing, differentiated nasopharyngeal carcinoma, an understudied but important subtype in Southeast Asian countries. This model adds to the limited number of authentic EBV-positive lines globally that will facilitate mechanistic studies and drug development for NPC.