USP31 Activates the Wnt/β-catenin Signaling Pathway and Promotes Gastric Cancer Cell Proliferation, Invasion and Migration.

Lan LiLimin YeYinying CuiYueting WuLing ShuiZheng ZongZhao Nie

Published in: Recent patents on anti-cancer drug discovery (2024)

USP31 inhibits ubiquitination of β-catenin by binding to it, stimulates the Wnt/β-- catenin pathway, activates glycolysis, and accelerates the biology of GCs, which are all demonstrated in this work.

Keyphrases

cell proliferation
cell cycle
pi k akt
stem cells
cell migration