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Field-applicable simultaneous multiplex LAMP assay for screening HBV and HCV co-infection in a single tube.

Hatice Esra AğelKevser Hanne Altın
Published in: BMC infectious diseases (2024)
The mLAMP assay displays significant promise for analyzing coinfected samples by simultaneously detecting the dual targets HBV and HCV within a set temperature of 62 °C, all within a time frame of 1 h. Additionally, when paired with disposable LFD, the mLAMP assay enables rapid visual detection of assay results in a matter of minutes. The result contributes to the mLAMP assay being highly suitable for coinfection screening, particularly in field conditions.
Keyphrases
  • high throughput
  • loop mediated isothermal amplification
  • hepatitis b virus
  • human immunodeficiency virus
  • machine learning
  • quantum dots
  • hiv infected
  • sensitive detection