Oxytocin receptor gene polymorphism and low serum oxytocin level are associated with hyperphagia and obesity in adolescents.
Gönül ÇatliSezer AcarGülten CingözKhayala RasulovaAyça Kanat YarimHamide UzunTuncay KümeSefa KızıldağBumin Nuri DündarAyhan AbacıPublished in: International journal of obesity (2005) (2021)
This study revealed that low serum OXT level, which is associated with hyperphagia may be an underlying cause for obesity in adolescents. For rs53576 polymorphism of the OXTR gene, obesity risk is higher in patients with homozygous mutant(G/G) and heterozygous(A/G)genotypes.