A rat arteriovenous graft model using decellularized vein.

Hualong BaiZhiwei WangMingxing LiPeng SunWang WangWeizhen LiuShunbo WeiZhiju WangYing XingAlan Dardik

Published in: Vascular (2020)

This model shows that decellularized vein can be successfully used as an arteriovenous graft between the rat aorta and the inferior vena cava. Several types of cells, including progenitor cells and macrophages, are present in the host response to these grafts in this model. This model can be used to test the application of arteriovenous grafts before conducting large animal experiments.

Keyphrases

inferior vena cava
pulmonary embolism
induced apoptosis
pulmonary artery
signaling pathway
cell death
pulmonary arterial hypertension
vena cava
tissue engineering