Molecular determinants and intracellular targets of taurine signalling in pancreatic islet β-cells.

Julie TurbittCharlotte R Moffett Lorraine BrennanPaul R V JohnsonPeter R Flatt Neville H McClenaghan Andrei I Tarasov

Published in: Acta physiologica (Oxford, England) (2024)

Together, these data demonstrate the pathways whereby taurine exhibits a range of beneficial effects on insulin secretion and β-cell function, consistent with the antidiabetic potential of its dietary low-dose supplementation.

Keyphrases

low dose
induced apoptosis
cell cycle arrest
high dose
electronic health record
big data
endoplasmic reticulum stress
reactive oxygen species
signaling pathway
oxidative stress
data analysis