LncRNA ASAP1-IT1 enhances cancer cell stemness via regulating miR-509-3p/YAP1 axis in NSCLC.

Yantao LiuYuping YangLingli ZhangJiaqiang LinBin LiMin YangHonghui LiKangwu ChenWei Zhao

Published in: Cancer cell international (2021)

YAP1-involved ASAP1-IT1/miR-509-3p axis promoted NSCLC progression by regulating cancer cell stemness, and targeting this signaling pathway could be is a promising therapeutic strategy to overcome NSCLC stemness.

Keyphrases

small cell lung cancer
epithelial mesenchymal transition
stem cells
advanced non small cell lung cancer
signaling pathway
brain metastases
cancer stem cells
pi k akt
epidermal growth factor receptor
cancer therapy