Exome-wide association study identifies four novel loci for systemic lupus erythematosus in Han Chinese population.

Leilei WenCaihong ZhuZhengwei ZhuChao YangXiaodong ZhengLu LiuXianbo ZuoYujun ShengHuayang TangBo LiangYi ZhouPan LiJun ZhuYantao DingGang ChenJinping GaoLili TangYuyan ChengJingying SunTamilselvi ElangoAnjana KafleRuixing YuKe XueYaohua ZhangFeng LiZhanguo LiJianping GuoXuan ZhangChen ZhouYuanjia TangNan ShenMeng WangXueqing YuShengxiu LiuXing FanMin GaoFengli XiaoPeiguang WangZaixing WangAnping ZhangFusheng ZhouLiangdan SunSen YangJinhua XuXianyong YinYong CuiXuejun Zhang

Published in: Annals of the rheumatic diseases (2017)

This study identified three novel coding variants and four new susceptibility gene regions for SLE. The results provide insights into the biological mechanism of SLE.

Keyphrases

systemic lupus erythematosus
genome wide
copy number
disease activity
rheumatoid arthritis
gene expression