Integrated associations of nasopharyngeal and serum metabolome with bronchiolitis severity and asthma: A multicenter prospective cohort study.

Michimasa FujiogiCarlos A CamargoYoshihiko RaitaZhaozhong ZhuJuan C CeledónJonathan M MansbachJonathan M SpergelKohei Hasegawa

Published in: Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology (2021)

In infants with bronchiolitis, we found integrated relationships of local and systemic metabolome networks with acute and chronic morbidity. Our findings advance research into the complex interplay among respiratory viruses, local and systemic response, and disease pathobiology in infants with bronchiolitis.

Keyphrases

respiratory syncytial virus
drug induced
liver failure
chronic obstructive pulmonary disease
lung function
respiratory failure
allergic rhinitis
intensive care unit
cystic fibrosis
hepatitis b virus
extracorporeal membrane oxygenation
acute respiratory distress syndrome