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Protein structure prediction from the complementary science perspective.

Jorge A Vila
Published in: Biophysical reviews (2023)
A comparative analysis between two problems-apparently unrelated-which are solved in a period of ~400 years, viz., the accurate prediction of both the planetary orbits and the protein structures, leads to inferred conjectures that go far beyond the existence of a common path in their resolution, i.e., observation → pattern recognition → modeling. The preliminary results from this analysis indicate that complementary science, together with a new perspective on protein folding, may help us discover common features that could contribute to a more in-depth understanding of still-unsolved problems such as protein folding.
Keyphrases
  • mental health
  • public health
  • single molecule
  • amino acid
  • binding protein
  • high resolution
  • molecular dynamics simulations
  • small molecule