Longitudinal evaluation of SARS-CoV-2 T cell immunity over 2 years following vaccination and infection.
Anna Karina JuhlLisa Loksø DietzOle Schmeltz SøgaardJoanne ReekieHenrik NielsenIsik Somuncu JohansenThomas Lars BenfieldLothar WieseNina Breinholt StærkeTomas Østergaard JensenRikke OlesenKasper Karmark IversenKamille FoghJacob BodilsenLone Wulff MadsenSusan Olaf LindvigDorthe RabenSidsel Dahl AndersenAstrid Korning HvidtSigne Rode AndreasenEva Anna Marianne BaerendsJens Dilling LundgrenLars ØstergaardMartin TolstrupPublished in: The Journal of infectious diseases (2024)
Our findings highlight the boosting effect on T cell immunity of repeated vaccine administration. The combination of multiple vaccine doses and SARS-CoV-2 infections maintains population T cell immunity although with reduced levels in the elderly.