Primary biliary cholangitis patients exhibit MRI changes in structure and function of interoceptive brain regions.

Victoria MosherMark SwainJack PangGilaad KaplanKeith SharkeyGlenda MacQueenBradley Gordon Goodyear

Published in: PloS one (2019)

PBC affects structure and function of brain regions critically important to interoception. Moreover, these brain changes occur in patients with early, milder disease and thus may potentially be reversible.

Keyphrases

resting state
white matter
end stage renal disease
functional connectivity
chronic kidney disease
newly diagnosed
ejection fraction
cerebral ischemia
magnetic resonance imaging
peritoneal dialysis
prognostic factors
patient reported outcomes
ulcerative colitis
subarachnoid hemorrhage