VCAM-1-targeted MRI Enables Detection of Brain Micrometastases from Different Primary Tumors.
Vinton W T ChengManuel Sarmiento SotoAlexandre A KhrapitchevFrancisco Perez-BalderasRasheed ZakariaMichael D JenkinsonMark Ross MiddletonNicola R SibsonPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2018)
VCAM-1-targeted MRI enables the detection of brain micrometastases from the three primary tumor types known to cause the majority of clinical cases. These findings represent an important step forward in the development of a broadly applicable and clinically relevant imaging technique for early diagnosis of brain metastasis, with significant implications for improved patient survival.
Keyphrases
- resting state
- white matter
- magnetic resonance imaging
- functional connectivity
- contrast enhanced
- cancer therapy
- cerebral ischemia
- loop mediated isothermal amplification
- high resolution
- real time pcr
- case report
- label free
- diffusion weighted imaging
- computed tomography
- magnetic resonance
- blood brain barrier
- photodynamic therapy
- quantum dots