Effects of resistance-associated variants in genotype 2 hepatitis C virus on viral replication and susceptibility to antihepatitis C virus drugs.

Goki SudaMegumi KimuraTaku ShigesawaKazuharu SuzukiAkihisa NakamuraMasatsugu OharaNaoki KawagishiMasato NakaiTakuya ShoOsamu MaeharaTomoe ShimazakiKenichi MorikawaMitsuteru NatsuizakaKoji OgawaNaoya Sakamoto

Published in: Hepatology research : the official journal of the Japan Society of Hepatology (2019)

When undertaking retreatment for genotype 2a HCV-infected patients who fail to respond to DAAs, the optimized retreatment should be chosen according to the sensitivity of the emerging RAVs to anti-HCV drugs.

Keyphrases

hepatitis c virus
human immunodeficiency virus
sars cov
copy number
gene expression
drug induced
hiv infected
antiretroviral therapy