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NAT8 Variants, N-Acetylated Amino Acids, and Progression of CKD.

Shengyuan LuoAditya SurapaneniZihe ZhengEugene P RheeJosef CoreshAdriana M HungGirish N NadkarniBing YuEric BoerwinkleAdrienne TinDan E ArkingInga SteinbrennerPascal SchlosserAnna KottgenMorgan E Grams
Published in: Clinical journal of the American Society of Nephrology : CJASN (2021)
We demonstrate significant associations between an NAT8 gene variant and 14 N-acetylated amino acids, five of which had circulation levels that were associated with kidney failure.
Keyphrases
  • amino acid
  • copy number
  • chronic kidney disease
  • genome wide
  • gene expression
  • dna methylation