NAT8 Variants, N-Acetylated Amino Acids, and Progression of CKD.
Shengyuan LuoAditya SurapaneniZihe ZhengEugene P RheeJosef CoreshAdriana M HungGirish N NadkarniBing YuEric BoerwinkleAdrienne TinDan E ArkingInga SteinbrennerPascal SchlosserAnna KottgenMorgan E GramsPublished in: Clinical journal of the American Society of Nephrology : CJASN (2021)
We demonstrate significant associations between an NAT8 gene variant and 14 N-acetylated amino acids, five of which had circulation levels that were associated with kidney failure.