Login / Signup

Renal toxicities associated with pembrolizumab.

Hassan IzzedineAlexis MathianStephane ChampiatCécile PicardChristine MateusEmilie RoutierAndrea VargaDavid MalkaAlexandra LearyJudith MichelsJean-Marie MichotAurélien MarabelleOlivier LambotteZahir AmouraJean-Charles SoriaSihem KaakiNathalie QuellardJean-Michel GoujonIsabelle Brocheriou
Published in: Clinical kidney journal (2018)
In our series, ATI, AIN and MCD are the most frequent forms of kidney involvement under pembrolizumab therapy. Kidney dysfunction is usually isolated but can be severe. Use of corticosteroids in case of AIN improves the glomerular filtration rate.
Keyphrases
  • advanced non small cell lung cancer
  • oxidative stress
  • early onset
  • epidermal growth factor receptor
  • mesenchymal stem cells
  • bone marrow
  • replacement therapy