Renal toxicities associated with pembrolizumab.
Hassan IzzedineAlexis MathianStephane ChampiatCécile PicardChristine MateusEmilie RoutierAndrea VargaDavid MalkaAlexandra LearyJudith MichelsJean-Marie MichotAurélien MarabelleOlivier LambotteZahir AmouraJean-Charles SoriaSihem KaakiNathalie QuellardJean-Michel GoujonIsabelle BrocheriouPublished in: Clinical kidney journal (2018)
In our series, ATI, AIN and MCD are the most frequent forms of kidney involvement under pembrolizumab therapy. Kidney dysfunction is usually isolated but can be severe. Use of corticosteroids in case of AIN improves the glomerular filtration rate.